What is in vitro fertilization (IVF)?

IVF is a procedure in which a woman’s eggs are fertilized with sperm in vitro (in the IVF laboratory).

The fertilized eggs are then transferred into the mother’s uterus or frozen and preserved for a future IVF procedure

How about Indications ?

Some common indications for IVF include advanced age related infertility, male factor including oligospermia, asthenospermia, teratospermia.

Previous damaged fallopian tubes, endometriosis And unexplained infertility, genetic testing for pregnancy loss or inheritable genetic diseases, and family balancing are also included.

How to do ?
  • Ovarian stimulation
  • Egg retrieval transvaginal ultrasound guidance
  • Fertilization in IVF Laboratory
  • Embryo transfer
Ovarian stimulation

The first step to IVF is ovarian stimulation or so called SuperOvulation.  

Using hormonal medications to stimulate the ovaries to grow eggs.

The medications are pills ex. Clomiphene, Letrozole and injections ex.

Gonal-F, Puregon, Elonva, Menopur, hMG… Over the course of those 10 days, you will be coming in to the IVF center every 2 or 3 days for ultrasounds and hormone measurements.

Monitor how you are responding and adjust the medications are necessary, and add medications when appropriate to prevent you from ovulating.

Egg retrieval Using Ultrasound guidance

While you are asleep and under anesthesia, a small needle is inserted into the ovaries to remove the eggs from your ovaries.

Typically this procedure takes 15 minutes While the retrieval is occurring, a well trained embryologist is there to look at and count the eggs.

Fertilization  in IVF Laboratory

The third step is fertilization. Sperm is collected via masturbation on the same day.

Following sperm wash,they are mixed with the eggs in the IVF lab. If IVF with Intro-Cytoplasmic Sperm Injection (ICSI) is used, the embryologist will inject a single, healthy sperm into each egg to increase the chances of successful fertilization.

The fertilized eggs are cultured in the lab for 2-5 days.

Embryo transfer
  • The embryo transfer is also an outpatient procedure done in our clinic.  Sedation is typically not required.

 

  • A thin catheter containing the embryo for transfer is inserted into the uterus through the cervix. Sono-guided is usually helpful
How many embryos will be transferred ?

Depend on the age of patient and embryo quality, one to two embryos were transferred often

In case, following PGTA genetically normal embryos, it will always be recommended that patients transfer one embryo at a time.